TerraPower Isotopes
Bill Gates-backed producer of actinium-225 from thorium-229, building a Philadelphia facility to raise supply 20-fold.
Overview
TerraPower Isotopes, based in Bellevue, Washington, is the Bill Gates-backed producer of actinium-225 from thorium-229, building a Philadelphia facility intended to raise supply twenty-fold. It obtains actinium-225 from the decay of thorium-229 recovered from a legacy uranium-233 stockpile and holds supply agreements with Bayer, Bristol Myers Squibb and others. Nuclide links it to targeted alpha therapy, alpha-emitter nanogenerators and the therapeutic isotope supply chain, to the radiopharmaceutical roadmap from iodine to actinium, and to the idea of recovering legacy radium-226 sources worldwide as feedstock. Manufacturing cost and time for radioactive medicines is the bottleneck it exists to relieve. Whether supply can grow fast enough for the alpha therapies now in phase 3 is the open question.
Manufacturing
Capacity map- TerraPower Isotopes Philadelphia Philadelphia, Pennsylvania, USRadioisotope production
Similar pages
not linked directly; found by shared links- CompanyOrano Med
Shares Recover legacy radium-226 sources worldwide as the feedstock for actinium-225, Actinium-225 supply, Isotope supply roadmap: reactor dependence → non-uranium production → accelerator-made actinium, Alpha-emitter roadmap: radium-223 → 225Ac-PSMA-617 → a phase 3 pipeline.
- CompanyNusano
Shares Isotope supply roadmap: reactor dependence → non-uranium production → accelerator-made actinium, Actinium-225 supply: thorium stocks, accelerators and radium targets, Therapeutic isotope supply chain (Mo-99, Lu-177, Ac-225), Actinium-225.
- CompanyNorthStar Medical Radioisotopes
Shares Actinium-225 supply, Isotope supply roadmap: reactor dependence → non-uranium production → accelerator-made actinium, Actinium-225 supply: thorium stocks, accelerators and radium targets, Therapeutic isotope supply chain (Mo-99, Lu-177, Ac-225).
- CompanyRayzeBio (BMS)
Shares Actinium-225 supply, Alpha-emitter roadmap: radium-223 → 225Ac-PSMA-617 → a phase 3 pipeline, Radiopharmaceutical roadmap: iodine → lutetium → actinium, Actinium-225 supply: thorium stocks, accelerators and radium targets.
- IdeaA global medical isotope supply observatory with forecasts and shortage alerts
Shares Actinium-225 supply, Isotope supply roadmap: reactor dependence → non-uranium production → accelerator-made actinium, Manufacturing cost and time for living and radioactive medicines, Targeted alpha therapy.
- AgentActinium-225 DOTATATE
Shares Recover legacy radium-226 sources worldwide as the feedstock for actinium-225, Actinium-225 supply, Alpha-emitter roadmap: radium-223 → 225Ac-PSMA-617 → a phase 3 pipeline, Radiopharmaceutical roadmap: iodine → lutetium → actinium.
- IdeaRegional cyclotron hubs for actinium-225 with an agreed actinium-227 impurity limit
Shares Actinium-225 supply, Manufacturing cost and time for living and radioactive medicines, Targeted alpha therapy, Actinium-225.
- CompanyFusion Pharmaceuticals (AstraZeneca)
Shares Alpha-emitter roadmap: radium-223 → 225Ac-PSMA-617 → a phase 3 pipeline, Radiopharmaceutical roadmap: iodine → lutetium → actinium, Targeted alpha therapy, Actinium-225.