Technetium Tc-99m sulfur colloid
Technetium sulfur colloid is the radioactive tracer injected around a breast cancer or melanoma before surgery so the surgeon can find the first lymph node the tumour drains to and remove only that node instead of the whole basin.
Overview
Technetium-99m sulfur colloid has been used for liver, spleen and bone marrow scintigraphy since the 1970s, and the FDA label was extended to lymphatic mapping to localise lymph nodes draining a primary breast tumour or melanoma. Sentinel node biopsy guided by the tracer, often with blue dye, replaced routine axillary dissection in breast cancer and elective node dissection in melanoma after the NSABP B-32 and MSLT-I trials, sparing most patients lymphoedema. Tilmanocept (Lymphoseek), a purpose-designed mannose receptor agent, is the newer alternative.
1.Technetium Tc-99m sulfur colloid binds its target on the cancer cell or is taken up by it.
Trials
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Latest papers
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Similar pages
not linked directly; found by shared links- TechnologyMolybdenum-99/technetium-99m generators
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- InstitutionJapanese Society of Nuclear Medicine
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- TermRadionuclidic purity
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- CompanyNiowave
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- AgentTechnetium-99m tilmanocept
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- TermRadiopharmacy (practice and discipline)
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- TermProduct release criteria (radiopharmaceutical quality control)
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- CompanyBWXT Medical
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