# Nuclide record temozolomide (drug). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/drugs/temozolomide/>
  a schema:Drug ;
  nuclide:kind "drug" ;
  schema:identifier "temozolomide" ;
  schema:name "Temozolomide"@en ;
  schema:description "The only chemotherapy proven to extend life in glioblastoma, given during and after radiation. It works best when the tumour has switched off a repair gene called MGMT."@en ;
  schema:url <https://nuclide.cc/drugs/temozolomide/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Temozolomide> ;
  owl:sameAs <http://www.wikidata.org/entity/Q425088> ;
  schema:citation <https://en.wikipedia.org/wiki/Temozolomide> ;
  nuclide:status "standard-of-care" ;
  nuclide:modality "Oral alkylating chemotherapy" ;
  schema:alternateName "Temodar" ;
  nuclide:approval "US 1999: Refractory anaplastic astrocytoma", "US 2005: Newly diagnosed glioblastoma with radiotherapy", "EU 1999: Temodal; malignant glioma (recurrent 1999; newly diagnosed glioblastoma with radiotherapy 2005); 26 Jan 1999" ;
  nuclide:indications <https://nuclide.cc/indications/glioblastoma/> ;
  nuclide:companies <https://nuclide.cc/companies/merck/> ;
  nuclide:trials <https://nuclide.cc/trials/nct04919226/> .