# Nuclide record tc-99m-pyrophosphate (drug). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/drugs/tc-99m-pyrophosphate/>
  a schema:Drug ;
  nuclide:kind "drug" ;
  schema:identifier "tc-99m-pyrophosphate" ;
  schema:name "Technetium Tc-99m pyrophosphate"@en ;
  schema:alternateName "Tc-99m PYP"@en, "PYP"@en, "Technescan PYP" ;
  schema:description "A bone-scanning radioactive tracer that also sticks to stray protein deposits that build up in a stiffened heart in transthyretin amyloidosis. Comparing how brightly the heart lights up against the ribs on the same scan tells doctors whether this specific, now-treatable type of heart disease is present, usually without needing a heart biopsy."@en ;
  schema:url <https://nuclide.cc/drugs/tc-99m-pyrophosphate/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/drugsatfda_docs/label/2025/017538s023,018321s026lbl.pdf>, <https://jamanetwork.com/journals/jamacardiology/fullarticle/2546034>, <https://www.asnc.org/wp-content/uploads/2024/05/ASNC-Practice-Point-99mTechnetium-Pyrophosphate.2016.pdf> ;
  nuclide:tag "SPECT", "cardiac amyloidosis", "bone-avid tracer" ;
  nuclide:modality "SPECT tracer" ;
  nuclide:approval "US 1976: Skeletal imaging to demonstrate areas of altered osteogenesis", "US 1976: Cardiac imaging as an adjunct in the diagnosis of acute myocardial infarction" ;
  nuclide:related <https://nuclide.cc/drugs/tl-201-chloride/>, <https://nuclide.cc/drugs/tc-99m-sestamibi/>, <https://nuclide.cc/isotopes/tc-99m/> ;
  nuclide:indications <https://nuclide.cc/indications/cardiac-amyloidosis-attr/> .