# Nuclide record tau-protein (target). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/targets/tau-protein/>
  a schema:BioChemEntity ;
  nuclide:kind "target" ;
  schema:identifier "tau-protein" ;
  schema:name "Tau protein (neurofibrillary tangles)"@en ;
  schema:alternateName "PHF-tau"@en, "aggregated tau"@en, "NFTs"@en ;
  schema:description "A protein that normally helps hold nerve cells together but, in Alzheimer's disease, twists into tangles inside the cells. A PET tracer called flortaucipir binds these tangles so doctors can see how far the disease has spread in the brain."@en ;
  schema:url <https://nuclide.cc/targets/tau-protein/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/drugsatfda_docs/label/2024/212123s031lbl.pdf>, <https://www.accessdata.fda.gov/drugsatfda_docs/nda/2020/212123Orig1s000IntegratedR.pdf>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC7911942/>, <https://investor.lilly.com/node/43256/pdf> ;
  nuclide:tag "neurology", "Alzheimer's disease", "protein aggregate" ;
  nuclide:targetClass "other" ;
  nuclide:related <https://nuclide.cc/targets/amyloid-beta/>, <https://nuclide.cc/isotopes/f-18/> .