# Nuclide record opp-cxcr4-primary-aldosteronism (opportunity). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/opportunities/opp-cxcr4-primary-aldosteronism/>
  a schema:CreativeWork ;
  nuclide:kind "opportunity" ;
  schema:identifier "opp-cxcr4-primary-aldosteronism" ;
  schema:name "CXCR4 imaging instead of adrenal vein sampling"@en ;
  schema:alternateName "PentixaFor PET"@en, "CXCR4 PET in primary aldosteronism"@en ;
  schema:description "A common and curable cause of high blood pressure is almost never cured, because finding out which adrenal gland is at fault needs an invasive procedure few hospitals do well. A PET scan can answer the same question, and one is now heading into a registrational trial."@en ;
  schema:url <https://nuclide.cc/opportunities/opp-cxcr4-primary-aldosteronism/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.nature.com/articles/s41591-022-02114-5>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC9936343/>, <https://www.eqs-news.com/news/corporate/pentixapharm-receives-fda-fast-track-designation-for-phase-3-diagnostic-candidate-e281b6e281b8gaga-pentixafor-in-primary-aldosteronism/239d14bc-6e9e-4077-9909-43e52edf7a09_en>, <https://www.pentixapharm.com/news/ema-grants-prime-status-to-pentixapharms-lead-candidate-pentixafor>, <https://jnm.snmjournals.org/content/56/3/410>, <https://www.endocrine.org/clinical-practice-guidelines/primary-aldosteronism-2> ;
  nuclide:tag "unmet need first", "standalone diagnostic", "non-oncology", "hypertension" ;
  nuclide:related <https://nuclide.cc/isotopes/ga-68/> ;
  nuclide:indications <https://nuclide.cc/indications/primary-aldosteronism/> ;
  nuclide:technologies <https://nuclide.cc/technologies/pet-ct/>, <https://nuclide.cc/technologies/pet/> ;
  nuclide:targets <https://nuclide.cc/targets/cxcr4/> ;
  nuclide:drugs <https://nuclide.cc/drugs/ga-68-pentixafor/> .