# Nuclide record opp-cldn18-2-imaging-gastric (opportunity). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/opportunities/opp-cldn18-2-imaging-gastric/>
  a schema:CreativeWork ;
  nuclide:kind "opportunity" ;
  schema:identifier "opp-cldn18-2-imaging-gastric" ;
  schema:name "Claudin-18.2 imaging when one biopsy says negative"@en ;
  schema:alternateName "CLDN18.2 PET"@en, "claudin 18.2 imaging"@en ;
  schema:description "Stomach cancer patients now get a drug only if a biopsy shows a protein called claudin-18.2. One biopsy core finds it only about six times in ten when the whole tumour has it, so patients are being refused a treatment on a test that misses."@en ;
  schema:url <https://nuclide.cc/opportunities/opp-cldn18-2-imaging-gastric/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.nature.com/articles/s41598-025-12337-4>, <https://link.springer.com/article/10.1007/s10120-024-01518-1>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC11149600/>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC12647276/>, <https://www.cancerbiomed.org/content/22/3/212> ;
  nuclide:tag "target crossover", "gastric", "companion diagnostic", "sampling error" ;
  nuclide:related <https://nuclide.cc/isotopes/ga-68/>, <https://nuclide.cc/isotopes/i-124/> ;
  nuclide:indications <https://nuclide.cc/indications/gastric-oesophageal-cancer/> ;
  nuclide:technologies <https://nuclide.cc/technologies/immuno-pet/>, <https://nuclide.cc/technologies/pet-ct/> ;
  nuclide:targets <https://nuclide.cc/targets/cldn18-2/> .