# Nuclide record lutathera (drug). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/drugs/lutathera/>
  a schema:Drug ;
  nuclide:kind "drug" ;
  schema:identifier "lutathera" ;
  schema:name "Lutetium-177 dotatate"@en ;
  schema:description "Lutetium-177 dotatate was the first modern radioligand therapy (2018), for neuroendocrine tumours, and is now used in first line."@en ;
  schema:url <https://nuclide.cc/drugs/lutathera/> ;
  schema:dateModified "2026-10-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Lutetium_(177Lu)_oxodotreotide> ;
  owl:sameAs <http://www.wikidata.org/entity/Q27273888> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Lutetium-177%20dotatate>, <https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=217060>, <https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2026/217060Orig1s000TAltr.pdf> ;
  nuclide:status "approved" ;
  nuclide:modality "Radioligand therapy (beta)" ;
  schema:alternateName "Lutathera" ;
  nuclide:approval "US 2018: SSTR+ GEP-NETs", "US 2024: Paediatric ≥12 years; first-line (NETTER-2 label)", "EU 2017: First approval globally (Sep 2017)" ;
  nuclide:related <https://nuclide.cc/isotopes/lu-177/> ;
  nuclide:indications <https://nuclide.cc/indications/neuroendocrine/>, <https://nuclide.cc/indications/small-intestinal-net/>, <https://nuclide.cc/indications/pancreatic-net/>, <https://nuclide.cc/indications/grade-3-net/>, <https://nuclide.cc/indications/metastatic-ppgl/> ;
  nuclide:technologies <https://nuclide.cc/technologies/radioligand-therapy/> ;
  nuclide:targets <https://nuclide.cc/targets/sstr2/> ;
  nuclide:companies <https://nuclide.cc/companies/novartis/> ;
  nuclide:terms <https://nuclide.cc/terms/prrt-term/> ;
  nuclide:trials <https://nuclide.cc/trials/netter-1/>, <https://nuclide.cc/trials/nct04711135/>, <https://nuclide.cc/trials/nct05142696/>, <https://nuclide.cc/trials/nct03972488/> .