# Nuclide record idea-pretargeted-alpha-therapy (idea). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/ideas/idea-pretargeted-alpha-therapy/>
  a schema:CreativeWork ;
  nuclide:kind "idea" ;
  schema:identifier "idea-pretargeted-alpha-therapy" ;
  schema:name "Pretargeted alpha radioimmunotherapy"@en ;
  schema:description "Instead of injecting a radioactive antibody that circulates in the blood for days, doctors first give a plain antibody that finds the tumour, wait for it to clear, then inject a small, fast-moving radioactive alpha payload that only attaches where the antibody is already waiting. This two-step trick could let radioactive antibodies treat solid tumours without poisoning the bone marrow."@en ;
  schema:url <https://nuclide.cc/ideas/idea-pretargeted-alpha-therapy/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://jnm.snmjournals.org/content/early/2025/06/05/jnumed.125.269601>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC12079710/>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC5824696/> ;
  nuclide:tag "alpha therapy", "antibody", "pretargeting" ;
  nuclide:related <https://nuclide.cc/technologies/targeted-alpha-therapy/>, <https://nuclide.cc/technologies/radioimmunotherapy/>, <https://nuclide.cc/targets/her2/>, <https://nuclide.cc/targets/ceacam5/>, <https://nuclide.cc/isotopes/lu-177/>, <https://nuclide.cc/isotopes/ac-225/>, <https://nuclide.cc/isotopes/i-131/>, <https://nuclide.cc/isotopes/bi-213/>, <https://nuclide.cc/isotopes/at-211/> .