# Nuclide record i-123-mibg-cardiac (drug). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/drugs/i-123-mibg-cardiac/>
  a schema:Drug ;
  nuclide:kind "drug" ;
  schema:identifier "i-123-mibg-cardiac" ;
  schema:name "Iobenguane I-123 (cardiac use)"@en ;
  schema:alternateName "I-123 MIBG"@en, "123I-mIBG"@en, "AdreView" ;
  schema:description "A radioactive tracer that mimics the body's own \"fight or flight\" nerve chemical and is taken up by the nerve endings in heart muscle. In people with heart failure, comparing how much of it the heart holds onto against the surrounding chest tissue gives a read on how damaged the heart's nerve supply is, which relates to future risk."@en ;
  schema:url <https://nuclide.cc/drugs/i-123-mibg-cardiac/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/022290s005lbl.pdf>, <https://www.accessdata.fda.gov/drugsatfda_docs/appletter/2013/022290orig1s001ltr.pdf> ;
  nuclide:tag "SPECT", "sympathetic innervation", "heart failure" ;
  nuclide:modality "SPECT tracer" ;
  nuclide:approval "US 2008: Detection of primary or metastatic pheochromocytoma or neuroblastoma as an adjunct to other diagnostic tests", "US 2013: Scintigraphic assessment of sympathetic innervation of the myocardium via heart-to-mediastinum ratio in NYHA class II-III heart failure with LVEF ≤ 35%, to help identify patients with lower 1- and 2-year mortality risk" ;
  nuclide:related <https://nuclide.cc/drugs/i131-mibg/>, <https://nuclide.cc/drugs/iobenguane-i-131/>, <https://nuclide.cc/technologies/mibg-theranostics/>, <https://nuclide.cc/isotopes/i-123/> .