# Nuclide record hif-vhl (pathway). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/pathways/hif-vhl/>
  a schema:BioChemEntity ;
  nuclide:kind "pathway" ;
  schema:identifier "hif-vhl" ;
  schema:name "VHL / HIF oxygen sensing"@en ;
  schema:description "The VHL/HIF pathway is how cells sense oxygen (the 2019 Nobel Prize). VHL destroys HIF when oxygen is present. Kidney cancers lose VHL, so HIF-2α is permanently on and drives blood vessel growth and proliferation."@en ;
  schema:url <https://nuclide.cc/pathways/hif-vhl/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Hypoxia-inducible_factor> ;
  owl:sameAs <http://www.wikidata.org/entity/Q415096> ;
  schema:citation <https://en.wikipedia.org/wiki/Hypoxia-inducible_factor> ;
  nuclide:related <https://nuclide.cc/isotopes/zr-89/> ;
  nuclide:indications <https://nuclide.cc/indications/rcc/> .