# Nuclide record her3 (target). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/targets/her3/>
  a schema:BioChemEntity ;
  nuclide:kind "target" ;
  schema:identifier "her3" ;
  schema:name "HER3 (ERBB3)"@en ;
  schema:alternateName "ERBB3"@en, "erb-b2 receptor tyrosine kinase 3"@en, "ERBB3" ;
  schema:description "A receptor on the surface of most lung cancer cells that helps tumours resist treatment. Drugs aimed at it exist, but measuring how much of it a tumour carries has so far failed to predict who benefits."@en ;
  schema:url <https://nuclide.cc/targets/her3/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  owl:sameAs <http://www.wikidata.org/entity/Q17917132> ;
  schema:citation <https://pmc.ncbi.nlm.nih.gov/articles/PMC12393064/>, <https://www.nature.com/articles/s41467-024-50056-y>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC12758208/>, <https://clinicaltrials.gov/study/NCT06222489> ;
  nuclide:tag "adc-target", "resistance", "lung" ;
  nuclide:targetClass "surface-antigen" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:3431>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000065361>, <https://www.uniprot.org/uniprotkb/P21860/entry>, <https://www.ncbi.nlm.nih.gov/gene/2065> ;
  nuclide:related <https://nuclide.cc/targets/her2/>, <https://nuclide.cc/opportunities/opp-her3-imaging-crossover/>, <https://nuclide.cc/isotopes/cu-64/>, <https://nuclide.cc/isotopes/zr-89/> ;
  nuclide:indications <https://nuclide.cc/indications/nsclc/> .