# Nuclide record dlg4-psd95 (target). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/targets/dlg4-psd95/>
  a schema:BioChemEntity ;
  nuclide:kind "target" ;
  schema:identifier "dlg4-psd95" ;
  schema:name "DLG4 (PSD-95)"@en ;
  schema:alternateName "PSD-95"@en, "PSD95"@en, "SAP90"@en, "postsynaptic density protein 95"@en, "DLG4"@en, "DLG4" ;
  schema:description "The main scaffold protein on the receiving side of brain synapses. Losing synapses tracks memory decline in Alzheimer's disease, but today's synapse PET scans only see the sending side (SV2A). No tracer for PSD-95 has been published, so the receiving side cannot yet be imaged."@en ;
  schema:url <https://nuclide.cc/targets/dlg4-psd95/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2903>, <https://pubmed.ncbi.nlm.nih.gov/38542104/>, <https://pubmed.ncbi.nlm.nih.gov/35461266/>, <https://pubmed.ncbi.nlm.nih.gov/?term=%28%22PSD-95%22%5Btiab%5D+OR+PSD95%5Btiab%5D+OR+DLG4%5Btiab%5D%29+AND+%28PET%5Btiab%5D+OR+radioligand%5Btiab%5D+OR+radiotracer%5Btiab%5D+OR+radiolabeled%5Btiab%5D+OR+radiolabelled%5Btiab%5D+OR+SPECT%5Btiab%5D%29> ;
  nuclide:tag "neurology", "synaptic density", "no tracer yet", "unmet need" ;
  nuclide:targetClass "other" ;
  nuclide:related <https://nuclide.cc/indications/alzheimers-disease/>, <https://nuclide.cc/targets/amyloid-beta/>, <https://nuclide.cc/targets/tau-protein/>, <https://nuclide.cc/technologies/pet/>, <https://nuclide.cc/isotopes/c-11/> ;
  nuclide:indications <https://nuclide.cc/indications/alzheimers-disease/> .