# Nuclide record dexrazoxane (drug). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/drugs/dexrazoxane/>
  a schema:Drug ;
  nuclide:kind "drug" ;
  schema:identifier "dexrazoxane" ;
  schema:name "Dexrazoxane"@en ;
  schema:alternateName "Cardioxane"@en, "Savene"@en, "Zinecard / Totect" ;
  schema:description "Dexrazoxane protects the heart from the cumulative damage of doxorubicin in women with metastatic breast cancer who need to keep receiving it, and, as Totect, limits tissue destruction when an anthracycline leaks out of a vein."@en ;
  schema:url <https://nuclide.cc/drugs/dexrazoxane/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Dexrazoxane> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=dexrazoxane>, <https://www.cancer.gov/about-cancer/treatment/drugs/dexrazoxanehydrochloride> ;
  nuclide:status "approved" ;
  nuclide:tag "nci-list", "supportive" ;
  nuclide:modality "Cardioprotectant and extravasation antidote (bisdioxopiperazine)" ;
  nuclide:approval "US 1995: Reduction of doxorubicin cardiomyopathy in women with metastatic breast cancer after 300 mg/m2 cumulative dose (Zinecard)", "US 2007: Anthracycline extravasation (Totect)" ;
  nuclide:companies <https://nuclide.cc/companies/pfizer/> .