# Nuclide record crossover (term). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/terms/crossover/>
  a schema:DefinedTerm ;
  nuclide:kind "term" ;
  schema:identifier "crossover" ;
  schema:name "Crossover in trials"@en ;
  schema:alternateName "cross-over"@en, "crossover-adjusted"@en, "crossover adjustment"@en, "adjusted for crossover"@en, "permitted crossover"@en, "crossover was permitted"@en, "crossover rate"@en, "post-progression therapy"@en, "subsequent therapy"@en, "subsequent treatment"@en, "RPSFT"@en, "rank-preserving structural failure time"@en, "IPCW"@en, "treatment switching"@en, "unplanned crossover"@en, "confounded by crossover"@en ;
  schema:description "When patients in a trial's control arm are allowed to switch to the experimental drug after their cancer progresses. It is fair to patients but blurs the survival comparison, because the control group has now had the drug too."@en ;
  schema:url <https://nuclide.cc/terms/crossover/> ;
  schema:dateModified "2026-09-09"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Crossover_study> ;
  schema:citation <https://en.wikipedia.org/wiki/Crossover_study> ;
  nuclide:related <https://nuclide.cc/terms/estimand/>, <https://nuclide.cc/isotopes/lu-177/> ;
  nuclide:trials <https://nuclide.cc/trials/vision/>, <https://nuclide.cc/trials/psmafore/>, <https://nuclide.cc/trials/therap/> .