# Nuclide record cldn18-2 (target). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/targets/cldn18-2/>
  a schema:BioChemEntity ;
  nuclide:kind "target" ;
  schema:identifier "cldn18-2" ;
  schema:name "Claudin-18.2"@en ;
  schema:alternateName "CLDN18.2"@en, "claudin 18 isoform 2"@en, "CLDN18"@en, "CLDN18" ;
  schema:description "A protein that seals the gaps between stomach lining cells. It stays on many stomach cancers as they spread, and two approved treatments are given only to patients whose biopsy shows it."@en ;
  schema:url <https://nuclide.cc/targets/cldn18-2/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  owl:sameAs <http://www.wikidata.org/entity/Q18040098> ;
  schema:citation <https://link.springer.com/article/10.1007/s10120-024-01518-1>, <https://www.nature.com/articles/s41598-025-12337-4>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC12647276/>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC11149600/>, <https://www.cancerbiomed.org/content/22/3/212> ;
  nuclide:tag "adc-target", "car-t-target", "companion diagnostic", "gastric" ;
  nuclide:targetClass "surface-antigen" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:2039>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000066405>, <https://www.uniprot.org/uniprotkb/P56856/entry>, <https://www.ncbi.nlm.nih.gov/gene/51208> ;
  nuclide:related <https://nuclide.cc/opportunities/opp-cldn18-2-imaging-gastric/>, <https://nuclide.cc/targets/her2/>, <https://nuclide.cc/isotopes/ga-68/>, <https://nuclide.cc/isotopes/i-124/> ;
  nuclide:indications <https://nuclide.cc/indications/gastric-oesophageal-cancer/> .