# Nuclide record beta-then-alpha (pairing). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/pairings/beta-then-alpha/>
  a schema:MedicalTherapy ;
  nuclide:kind "pairing" ;
  schema:identifier "beta-then-alpha" ;
  schema:name "Beta radioligand → alpha radioligand"@en ;
  schema:description "After lutetium therapy stops working, an actinium version of the same drug can still produce responses."@en ;
  schema:url <https://nuclide.cc/pairings/beta-then-alpha/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT06402331> ;
  nuclide:related <https://nuclide.cc/isotopes/lu-177/>, <https://nuclide.cc/isotopes/ac-225/> ;
  nuclide:indications <https://nuclide.cc/indications/prostate/>, <https://nuclide.cc/indications/neuroendocrine/> ;
  nuclide:drugs <https://nuclide.cc/drugs/pluvicto/>, <https://nuclide.cc/drugs/ac225-psma/>, <https://nuclide.cc/drugs/lutathera/>, <https://nuclide.cc/drugs/ryz101/> ;
  nuclide:terms <https://nuclide.cc/terms/alpha-vs-beta/> ;
  nuclide:pairs <https://nuclide.cc/technologies/radioligand-therapy/>, <https://nuclide.cc/technologies/targeted-alpha-therapy/> .