# Nuclide record b-manufacturing-cell-therapy (bottleneck). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/bottlenecks/b-manufacturing-cell-therapy/>
  a schema:Thing ;
  nuclide:kind "bottleneck" ;
  schema:identifier "b-manufacturing-cell-therapy" ;
  schema:name "Manufacturing cost and time for living and radioactive medicines"@en ;
  schema:description "Cell therapies take weeks to make for one patient and cost hundreds of thousands of dollars. Isotopes run short."@en ;
  schema:url <https://nuclide.cc/bottlenecks/b-manufacturing-cell-therapy/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:citation <https://doi.org/10.1001/jamaoncol.2018.0977>, <https://doi.org/10.1056/NEJMoa1709866>, <https://www.isotopes.gov/> ;
  nuclide:related <https://nuclide.cc/roadmaps/radiopharma-roadmap/>, <https://nuclide.cc/ideas/idea-reg-legacy-radium-recovery-ac225/>, <https://nuclide.cc/ideas/idea-reg-ac225-accelerator-pharmacopoeia/>, <https://nuclide.cc/ideas/idea-reg-yb176-enrichment-capacity/>, <https://nuclide.cc/ideas/idea-reg-medical-isotope-reactor-reserve/>, <https://nuclide.cc/ideas/idea-reg-alpha-emitter-portfolio/>, <https://nuclide.cc/ideas/idea-reg-regional-radiopharmacy-hubs/>, <https://nuclide.cc/ideas/idea-reg-isotope-supply-observatory/>, <https://nuclide.cc/isotopes/lu-177/>, <https://nuclide.cc/isotopes/ac-225/> ;
  nuclide:indications <https://nuclide.cc/indications/dlbcl/>, <https://nuclide.cc/indications/prostate/>, <https://nuclide.cc/indications/neuroendocrine/> ;
  nuclide:technologies <https://nuclide.cc/technologies/radioligand-therapy/>, <https://nuclide.cc/technologies/targeted-alpha-therapy/> ;
  nuclide:drugs <https://nuclide.cc/drugs/pluvicto/>, <https://nuclide.cc/drugs/lutathera/>, <https://nuclide.cc/drugs/ac225-psma/> ;
  nuclide:companies <https://nuclide.cc/companies/novartis/>, <https://nuclide.cc/companies/terrapower-isotopes/>, <https://nuclide.cc/companies/orano-med/>, <https://nuclide.cc/companies/itm/>, <https://nuclide.cc/companies/curium/> ;
  nuclide:terms <https://nuclide.cc/terms/alpha-vs-beta/>, <https://nuclide.cc/terms/dosimetry/>, <https://nuclide.cc/terms/theranostics/> ;
  nuclide:trials <https://nuclide.cc/trials/vision/> .