# Nuclide record alpha-synuclein (target). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/targets/alpha-synuclein/>
  a schema:BioChemEntity ;
  nuclide:kind "target" ;
  schema:identifier "alpha-synuclein" ;
  schema:name "Alpha-synuclein"@en ;
  schema:alternateName "a-synuclein"@en, "SNCA"@en, "alpha synuclein aggregates"@en, "SNCA" ;
  schema:description "The protein that clumps inside brain cells in Parkinson's disease and related conditions. Nobody can yet see those clumps in a living person, which is why these diseases are still diagnosed by watching the patient."@en ;
  schema:url <https://nuclide.cc/targets/alpha-synuclein/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://pmc.ncbi.nlm.nih.gov/articles/PMC10611796/>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC13121216/>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC8466155/>, <https://www.movementdisorders.org/MDS/Scientific-Issues/posts/The-past-present-and-future-roles-of-a-synuclein-seed-amplification-assays.htm>, <https://www.alzforum.org/news/conference-coverage/first-field-synuclein-pet-only-multiple-system-atrophy> ;
  nuclide:tag "neurology", "protein aggregate", "unmet need" ;
  nuclide:targetClass "other" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:11138>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000145335>, <https://www.uniprot.org/uniprotkb/P37840/entry>, <https://www.ncbi.nlm.nih.gov/gene/6622> ;
  nuclide:related <https://nuclide.cc/targets/tau-protein/>, <https://nuclide.cc/targets/amyloid-beta/>, <https://nuclide.cc/opportunities/opp-alpha-synuclein-pet-parkinsons/>, <https://nuclide.cc/isotopes/f-18/> ;
  nuclide:indications <https://nuclide.cc/indications/parkinsonian-syndromes/> .