# Nuclide record alpha-daughter-redistribution (technology). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)". Whole corpus: https://nuclide.cc/api/v1/nuclide.nt
@prefix schema: <https://schema.org/> .
@prefix nuclide: <https://nuclide.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://nuclide.cc/technologies/alpha-daughter-redistribution/>
  a schema:MedicalTherapy ;
  nuclide:kind "technology" ;
  schema:identifier "alpha-daughter-redistribution" ;
  schema:name "Alpha-emitter daughter redistribution ('free daughter' problem)"@en ;
  schema:alternateName "nuclear recoil effect"@en, "free daughter problem"@en ;
  schema:description "When an alpha-emitting radioactive drug decays inside the body, the recoil kick is so strong that the leftover radioactive fragment breaks loose from the drug and can drift to organs like the kidneys, causing side effects the original drug was never meant to cause."@en ;
  schema:url <https://nuclide.cc/technologies/alpha-daughter-redistribution/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://www.mdpi.com/2072-6694/17/18/3055>, <https://www.thno.org/v14p2969.htm>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC6690960/>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC12660422/>, <https://pmc.ncbi.nlm.nih.gov/articles/PMC9966725/>, <https://www.mdpi.com/1424-8247/18/10/1578> ;
  nuclide:tag "alpha therapy", "chemistry", "toxicity" ;
  nuclide:related <https://nuclide.cc/technologies/targeted-alpha-therapy/>, <https://nuclide.cc/technologies/macropa-chelation/>, <https://nuclide.cc/technologies/alpha-nanogenerators/>, <https://nuclide.cc/drugs/ac225-psma/>, <https://nuclide.cc/drugs/alphamedix/>, <https://nuclide.cc/isotopes/ac-225/>, <https://nuclide.cc/isotopes/pb-212/>, <https://nuclide.cc/isotopes/bi-213/> ;
  nuclide:dependsOn <https://nuclide.cc/technologies/targeted-alpha-therapy/>, <https://nuclide.cc/technologies/macropa-chelation/> .