{"entity":{"id":"ntp-radioisotopes","kind":"company","name":"NTP Radioisotopes","aka":["NTP"],"tldr":"NTP, part of South Africa's state nuclear corporation, processes molybdenum-99 and other isotopes from the SAFARI-1 reactor and was the first major producer to switch to low-enriched uranium targets.","summary":"NTP Radioisotopes, a subsidiary of the South African Nuclear Energy Corporation, irradiates targets in the SAFARI-1 research reactor at Pelindaba and processes molybdenum-99, iodine-131 and lutetium-177 for export to generator makers and radiopharmacies worldwide. It converted its molybdenum production to low-enriched uranium targets ahead of other producers. Regulator-ordered shutdowns of its processing facility in 2017 and 2018 removed a large share of world molybdenum-99 supply for months and showed how few processors there are.","asOf":"2026-09-17","links":[{"label":"Official website","url":"https://www.ntp.co.za"}],"tags":["manufacturing-wave"],"related":["mo-99","lu-177","i-131"],"indications":[],"sections":[],"technologies":["research-reactor-isotope-production","therapy-isotope-supply-chain"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Pelindaba, near Pretoria","country":"ZA","companyType":"radiopharma","website":"https://www.ntp.co.za","stage":"private-large","investors":[],"funding":[]},"route":"/companies/ntp-radioisotopes/","neighbours":{"isotope":[{"id":"i-131","kind":"isotope","name":"Iodine-131","route":"/isotopes/i-131/"},{"id":"lu-177","kind":"isotope","name":"Lutetium-177","route":"/isotopes/lu-177/"},{"id":"mo-99","kind":"isotope","name":"Molybdenum-99","route":"/isotopes/mo-99/"}],"technology":[{"id":"research-reactor-isotope-production","kind":"technology","name":"Research reactors for medical isotopes (Mo-99, Lu-177, I-131)","route":"/technologies/research-reactor-isotope-production/"},{"id":"therapy-isotope-supply-chain","kind":"technology","name":"Therapeutic isotope supply chain (Mo-99, Lu-177, Ac-225)","route":"/technologies/therapy-isotope-supply-chain/"}],"bottleneck":[{"id":"b-enriched-target-material","kind":"bottleneck","name":"Enriched target material for therapeutic isotopes","route":"/bottlenecks/b-enriched-target-material/"},{"id":"b-mo99-supply","kind":"bottleneck","name":"Molybdenum-99 supply","route":"/bottlenecks/b-mo99-supply/"}],"roadmap":[{"id":"isotope-supply-roadmap","kind":"roadmap","name":"Isotope supply roadmap: reactor dependence → non-uranium production → accelerator-made actinium","route":"/roadmaps/isotope-supply-roadmap/"}]}}