# Robert H. Mach

Source: https://nuclide.cc/people/robert-mach/  
Nuclide record `robert-mach` (Person). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)"; commercial use needs a licence.

## TL;DR

Robert Mach invented the PARP PET tracer FluorThanatrace that images DNA repair capacity in tumours.

## Summary

Robert H. Mach is the Britton Chance Professor of Radiology and Director of PET Radiochemistry at the Abramson Cancer Center, University of Pennsylvania. He is a radiochemist known for inventing the PARP PET tracer fluorine-18 FluorThanatrace, which images DNA repair capacity in tumours, alongside other tracers for imaging drug targets. His selected paper reports FluorThanatrace uptake as a marker of PARP1 expression and activity in breast cancer. His laboratory's tracers enable PARP-inhibitor patient selection studies and molecular imaging with PET.

## Fields

- Kind: Person
- Last checked: 2026-09-08
- Role: Britton Chance Professor of Radiology; Director, PET Radiochemistry
- Specialisms: Radiochemistry; PARP PET; Molecular imaging

## Sources

- PubMed: https://pubmed.ncbi.nlm.nih.gov/?term=Mach%20RH%5BAuthor%5D

## Connected records

- isotopes: [Fluorine-18](https://nuclide.cc/isotopes/f-18/)
- technologies: [PARP PET](https://nuclide.cc/technologies/parp-pet/), [PET (positron emission tomography)](https://nuclide.cc/technologies/pet/)
- targets: [PARP](https://nuclide.cc/targets/parp/)
- institutions: [Abramson Cancer Center, University of Pennsylvania](https://nuclide.cc/institutions/penn-abramson/)

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