# NorthStar Medical Radioisotopes

Source: https://nuclide.cc/companies/northstar-medical-radioisotopes/  
Nuclide record `northstar-medical-radioisotopes` (Company). Data CC BY-NC 4.0, attribute "Data from Nuclide (nuclide.cc)"; commercial use needs a licence.

## TL;DR

NorthStar is a non-reactor producer of Mo-99 in the US and an emerging supplier of non-carrier-added Lu-177 and Ac-225 made with electron accelerators.

## Summary

NorthStar Medical Radioisotopes, based in Beloit, Wisconsin, is a non-reactor producer of molybdenum-99 in the United States and an emerging supplier of non-carrier-added lutetium-177 and actinium-225 made with electron accelerators. Its RadioGenix Mo-99 system was approved in 2018, its accelerator-based actinium-225 production facility came online in 2024 to 2025, and it holds lutetium-177 supply agreements. Nuclide links it to the therapeutic isotope supply chain for Mo-99, Lu-177 and Ac-225. Whether accelerator production can supply actinium-225 at the volumes the alpha therapies in phase 3 will need is the open question. The isotope supply chain page carries the wider picture.

## Fields

- Kind: Company
- Last checked: 2026-09-08
- Tags: supporting
- HQ: Beloit, WI
- Type: radiopharma
- Website: https://www.northstarnm.com

## Sources

- Official website: https://www.northstarnm.com

## Connected records

- isotopes: [Actinium-225](https://nuclide.cc/isotopes/ac-225/), [Lutetium-177](https://nuclide.cc/isotopes/lu-177/), [Molybdenum-99](https://nuclide.cc/isotopes/mo-99/)
- technologies: [Actinium-225 supply: thorium stocks, accelerators and radium targets](https://nuclide.cc/technologies/actinium-225-supply/), [Research reactors for medical isotopes (Mo-99, Lu-177, I-131)](https://nuclide.cc/technologies/research-reactor-isotope-production/), [Therapeutic isotope supply chain (Mo-99, Lu-177, Ac-225)](https://nuclide.cc/technologies/therapy-isotope-supply-chain/)
- bottlenecks: [Actinium-225 supply](https://nuclide.cc/bottlenecks/b-ac225-supply/), [Molybdenum-99 supply](https://nuclide.cc/bottlenecks/b-mo99-supply/)
- fronts: [Isotope supply](https://nuclide.cc/fronts/f-isotope-supply/)
- ideas: [Scaling actinium-225 supply with proton accelerators instead of the thorium-229 cow](https://nuclide.cc/ideas/idea-accelerator-ac225-at-scale/)
- roadmaps: [Isotope supply roadmap: reactor dependence → non-uranium production → accelerator-made actinium](https://nuclide.cc/roadmaps/isotope-supply-roadmap/)

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